[Preliminary analyses on bacterial diversity and resistance in infection-related skin disorders].

Abstract

OBJECTIVE To explore the bacterial diversity and resistance in infection-related skin disorders. METHODS The samples of blood, pyogenic fluid, exudate and skin dander were collected from 54 outpatients of chronic and recurrent skin disease and cultured for positive pathogens in the dermatological department of Peking University Third hospital from March 2010 to May 2011. Also their drug susceptibilities were examined. RESULTS Among 63 bacterial strains of 22 species in 12 genus, the pathogens were Staphylococcus epidermidis, Staphylococcus aureus, Micrococcus luteus, group A Streptococcus pyogenes, Staphylococcus agalactiae, Corynebacterium sp., Bacillus subtilis, Bacillus cereus, Acinetobacter baumanii, A. lwoffii, Pseudomonas aeruginosa, Enterobacter cloacae, Rhizobium radiobacter, Sphingomonas paucimobilis, Enterococcus faecalis, Neisseria sicca and Neisseria gonorrhoeae. The percentage of methicillin-resistant coagulase negative staphylococci (MRCNS) was 46.4% (13/28) while the resistant rates of Styphylococci to ampicillin, penicillin, azithromycin, cefoxitin, clindamycin and SMZ-TMP were 88.6% (31/35), 88.6% (31/35), 68.6% (24/35), 37.1 (13/35), 28.6(10/35) and 26.5 (9/34) respectively. Gram negative bacilli were sensitive to ampicillin, amikacin sulfate, ceftazidime. CONCLUSION There are a wide range of pathogenic bacterial species among refractory infection of outpatients. And drug resistance is among the reasons for refractory infections.

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